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Spatial Principles of Chromatin Architecture Associated With Organ-Specific Gene Regulation
Packaging of the genome in the nucleus is a non-random process that is thought to directly contribute to cell type-specific transcriptomes, although this hypothesis remains untested. Epigenome architecture, as assayed by chromatin conformation capture techniques, such as Hi-C, has recently been desc...
Autores principales: | Chapski, Douglas J., Rosa-Garrido, Manuel, Hua, Nan, Alber, Frank, Vondriska, Thomas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341059/ https://www.ncbi.nlm.nih.gov/pubmed/30697540 http://dx.doi.org/10.3389/fcvm.2018.00186 |
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