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Microbiome networks and change-point analysis reveal key community changes associated with cystic fibrosis pulmonary exacerbations

Over 90% of cystic fibrosis (CF) patients die due to chronic lung infections leading to respiratory failure. The decline in CF lung function is greatly accelerated by intermittent and progressively severe acute pulmonary exacerbations (PEs). Despite their clinical impact, surprisingly few microbiolo...

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Detalles Bibliográficos
Autores principales: Layeghifard, Mehdi, Li, Hannah, Wang, Pauline W., Donaldson, Sylva L., Coburn, Bryan, Clark, Shawn T., Caballero, Julio Diaz, Zhang, Yu, Tullis, D. Elizabeth, Yau, Yvonne C. W., Waters, Valerie, Hwang, David M., Guttman, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341074/
https://www.ncbi.nlm.nih.gov/pubmed/30675371
http://dx.doi.org/10.1038/s41522-018-0077-y