Abnormal ER quality control of neural GPI-anchored proteins via dysfunction in ER export processing in the frontal cortex of elderly subjects with schizophrenia

Abnormalities of posttranslational protein modifications (PTMs) have recently been implicated in the pathophysiology of schizophrenia. Glycosylphosphatidylinositols (GPIs) are a class of complex glycolipids, which anchor surface proteins and glycoproteins to the cell membrane. GPI attachment to prot...

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Detalles Bibliográficos
Autores principales: Kim, Pitna, Scott, Madeline R., Meador-Woodruff, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341114/
https://www.ncbi.nlm.nih.gov/pubmed/30664618
http://dx.doi.org/10.1038/s41398-018-0359-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341114/
https://www.ncbi.nlm.nih.gov/pubmed/30664618
http://dx.doi.org/10.1038/s41398-018-0359-4

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