Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

In humans, genetic variants of DLGAP1-4 have been linked with neuropsychiatric conditions, including autism spectrum disorder (ASD). While these findings implicate the encoded postsynaptic proteins, SAPAP1-4, in the etiology of neuropsychiatric conditions, underlying neurobiological mechanisms are u...

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Detalles Bibliográficos
Autores principales: Schob, Claudia, Morellini, Fabio, Ohana, Ora, Bakota, Lidia, Hrynchak, Mariya V., Brandt, Roland, Brockmann, Marco D., Cichon, Nicole, Hartung, Henrike, Hanganu-Opatz, Ileana L., Kraus, Vanessa, Scharf, Sarah, Herrmans-Borgmeyer, Irm, Schweizer, Michaela, Kuhl, Dietmar, Wöhr, Markus, Vörckel, Karl J., Calzada-Wack, Julia, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabě de Angelis, Martin, Garner, Craig C., Kreienkamp, Hans-Jürgen, Kindler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341115/
https://www.ncbi.nlm.nih.gov/pubmed/30664629
http://dx.doi.org/10.1038/s41398-018-0327-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341115/
https://www.ncbi.nlm.nih.gov/pubmed/30664629
http://dx.doi.org/10.1038/s41398-018-0327-z

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