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Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice
In humans, genetic variants of DLGAP1-4 have been linked with neuropsychiatric conditions, including autism spectrum disorder (ASD). While these findings implicate the encoded postsynaptic proteins, SAPAP1-4, in the etiology of neuropsychiatric conditions, underlying neurobiological mechanisms are u...
Autores principales: | Schob, Claudia, Morellini, Fabio, Ohana, Ora, Bakota, Lidia, Hrynchak, Mariya V., Brandt, Roland, Brockmann, Marco D., Cichon, Nicole, Hartung, Henrike, Hanganu-Opatz, Ileana L., Kraus, Vanessa, Scharf, Sarah, Herrmans-Borgmeyer, Irm, Schweizer, Michaela, Kuhl, Dietmar, Wöhr, Markus, Vörckel, Karl J., Calzada-Wack, Julia, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabě de Angelis, Martin, Garner, Craig C., Kreienkamp, Hans-Jürgen, Kindler, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341115/ https://www.ncbi.nlm.nih.gov/pubmed/30664629 http://dx.doi.org/10.1038/s41398-018-0327-z |
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