A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies

Comprehensive preclinical studies of Myelodysplastic Syndromes (MDS) have been elusive due to limited ability of MDS stem cells to engraft current immunodeficient murine hosts. Here we report a MDS patient-derived xenotransplantation model in cytokine-humanized immunodeficient “MISTRG” mice that pro...

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Detalles Bibliográficos
Autores principales: Song, Yuanbin, Rongvaux, Anthony, Taylor, Ashley, Jiang, Tingting, Tebaldi, Toma, Balasubramanian, Kunthavai, Bagale, Arun, Terzi, Yunus Kasim, Gbyli, Rana, Wang, Xiaman, Fu, Xiaoying, Gao, Yimeng, Zhao, Jun, Podoltsev, Nikolai, Xu, Mina, Neparidze, Natalia, Wong, Ellice, Torres, Richard, Bruscia, Emanuela M., Kluger, Yuval, Manz, Markus G., Flavell, Richard A., Halene, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341122/
https://www.ncbi.nlm.nih.gov/pubmed/30664659
http://dx.doi.org/10.1038/s41467-018-08166-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341122/
https://www.ncbi.nlm.nih.gov/pubmed/30664659
http://dx.doi.org/10.1038/s41467-018-08166-x

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