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A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies
Comprehensive preclinical studies of Myelodysplastic Syndromes (MDS) have been elusive due to limited ability of MDS stem cells to engraft current immunodeficient murine hosts. Here we report a MDS patient-derived xenotransplantation model in cytokine-humanized immunodeficient “MISTRG” mice that pro...
Autores principales: | Song, Yuanbin, Rongvaux, Anthony, Taylor, Ashley, Jiang, Tingting, Tebaldi, Toma, Balasubramanian, Kunthavai, Bagale, Arun, Terzi, Yunus Kasim, Gbyli, Rana, Wang, Xiaman, Fu, Xiaoying, Gao, Yimeng, Zhao, Jun, Podoltsev, Nikolai, Xu, Mina, Neparidze, Natalia, Wong, Ellice, Torres, Richard, Bruscia, Emanuela M., Kluger, Yuval, Manz, Markus G., Flavell, Richard A., Halene, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341122/ https://www.ncbi.nlm.nih.gov/pubmed/30664659 http://dx.doi.org/10.1038/s41467-018-08166-x |
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