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Genotoxicity and pharmacokinetic characterization of Cereus jamacaru ethanolic extract in rats

The effect of Cereus jamacaru ethanolic extract in rats was analyzed using genotoxicity assays and liver ABCB1 and CYP2D4 gene expression. The lyophilized extract of C. jamacaru cladodes was analyzed with LC–MS/MS. Male Wistar rats (n=36) were equally distributed into six groups that did (+) or did...

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Detalles Bibliográficos
Autores principales: de Medeiros, Iris Ucella, de Medeiros, Rhoza Araújo, Bortolin, Raul Henandes, de Queiroz, Fernando Márlisson, Silbiger, Vivian Nogueira, Pflugmacher, Stephan, Schwarz, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341123/
https://www.ncbi.nlm.nih.gov/pubmed/30563925
http://dx.doi.org/10.1042/BSR20180672