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Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery

INTRODUCTION: Postoperative morbidity and mortality in older patients with comorbidities undergoing gastrointestinal surgery are a major burden on healthcare systems. Infections after surgery are common in such patients, prolonging hospitalisation and reducing postoperative short-term and long-term...

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Detalles Bibliográficos
Autores principales: Edwards, Mark R, Forbes, Gordon, MacDonald, Neil, Berdunov, Vladislav, Mihaylova, Borislava, Dias, Priyanthi, Thomson, Ann, Grocott, Michael PW, Mythen, Monty G, Gillies, Mike A, Sander, Michael, Phan, Tuong D, Evered, Lisbeth, Wijeysundera, Duminda N, McCluskey, Stuart A, Aldecoa, Cesar, Ripollés-Melchor, Javier, Hofer, Christoph K, Abukhudair, Hussein, Szczeklik, Wojciech, Grigoras, Ioana, Hajjar, Ludhmila A, Kahan, Brennan C, Pearse, Rupert M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341180/
https://www.ncbi.nlm.nih.gov/pubmed/30647034
http://dx.doi.org/10.1136/bmjopen-2018-023455