IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

Candidate vaccines designed to generate T cell–based immunity are typically vectored by nonpersistent viruses, which largely fail to elicit durable effector memory T cell responses. This limitation can be overcome using recombinant strains of CMV. Proof-of-principle studies have demonstrated the pot...

Descripción completa

Detalles Bibliográficos
Autores principales: McLaren, James E., Clement, Mathew, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J., Ladell, Kristin, Price, David A., Humphreys, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2019
Materias:
Mucosal Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341181/
https://www.ncbi.nlm.nih.gov/pubmed/30635396
http://dx.doi.org/10.4049/jimmunol.1701757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341181/
https://www.ncbi.nlm.nih.gov/pubmed/30635396
http://dx.doi.org/10.4049/jimmunol.1701757

Ejemplares similares