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The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the loss of motor neurons. Its etiology remains unknown, but several pathophysiological mechanisms are beginning to explain motor neuronal death, as well as oxidative stress. Iron accumulation has been observed in both spor...

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Detalles Bibliográficos
Autores principales: Petillon, Camille, Hergesheimer, Rudolf, Puy, Hervé, Corcia, Philippe, Vourc’h, Patrick, Andres, Christian, Karim, Zoubida, Blasco, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341213/
https://www.ncbi.nlm.nih.gov/pubmed/30697143
http://dx.doi.org/10.3389/fnins.2018.01031