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Constraints on GPCR Heterodimerization Revealed by the Type-4 Induced-Association BRET Assay

G-protein-coupled receptors (GPCRs) comprise the largest and most pharmacologically important family of cell-surface receptors encoded by the human genome. In many instances, the distinct signaling behavior of certain GPCRs has been explained in terms of the formation of heteromers with, for example...

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Detalles Bibliográficos
Autores principales: Felce, James H., MacRae, Alasdair, Davis, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341220/
https://www.ncbi.nlm.nih.gov/pubmed/30558888
http://dx.doi.org/10.1016/j.bpj.2018.09.034