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Constraints on GPCR Heterodimerization Revealed by the Type-4 Induced-Association BRET Assay
G-protein-coupled receptors (GPCRs) comprise the largest and most pharmacologically important family of cell-surface receptors encoded by the human genome. In many instances, the distinct signaling behavior of certain GPCRs has been explained in terms of the formation of heteromers with, for example...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341220/ https://www.ncbi.nlm.nih.gov/pubmed/30558888 http://dx.doi.org/10.1016/j.bpj.2018.09.034 |