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Expression of Sclerostin in Osteoporotic Fracture Patients Is Associated with DNA Methylation in the CpG Island of the SOST Gene

PURPOSE: SOST gene is one of the key factors in regulating bone absorption. Although there are reports showing diverse transcription factors, epigenetic modification could be responsible for regulating SOST gene expression. There is still little exploration on promoter methylation status of SOST gen...

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Detalles Bibliográficos
Autores principales: Cao, Yanming, Wang, Bin, Wang, Ding, Zhan, Dongxiang, Mai, Caiyuan, Wang, Peng, Wei, Qiushi, Liu, Yamei, Wang, Haibin, He, Wei, Xu, Liangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341240/
https://www.ncbi.nlm.nih.gov/pubmed/30729116
http://dx.doi.org/10.1155/2019/7076513