Cargando…
Expression of Sclerostin in Osteoporotic Fracture Patients Is Associated with DNA Methylation in the CpG Island of the SOST Gene
PURPOSE: SOST gene is one of the key factors in regulating bone absorption. Although there are reports showing diverse transcription factors, epigenetic modification could be responsible for regulating SOST gene expression. There is still little exploration on promoter methylation status of SOST gen...
Autores principales: | Cao, Yanming, Wang, Bin, Wang, Ding, Zhan, Dongxiang, Mai, Caiyuan, Wang, Peng, Wei, Qiushi, Liu, Yamei, Wang, Haibin, He, Wei, Xu, Liangliang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341240/ https://www.ncbi.nlm.nih.gov/pubmed/30729116 http://dx.doi.org/10.1155/2019/7076513 |
Ejemplares similares
-
DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter
por: Papathanasiou, Ioanna, et al.
Publicado: (2015) -
Expression of SOST/sclerostin in compressed periodontal ligament cells
por: Ueda, Masae, et al.
Publicado: (2016) -
Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016) -
Factors to preserve CpG-rich sequences in methylated CpG islands
por: Miyahara, Hiroki, et al.
Publicado: (2015) -
Influence of DNA methylation on the expression of OPG/RANKL in primary osteoporosis
por: Wang, Peng, et al.
Publicado: (2018)