Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes

OBJECTIVE: Abnormally elevated proinsulin secretion has been reported in type 2 and early type 1 diabetes when significant C-peptide is present. We questioned whether individuals with long-standing type 1 diabetes and low or absent C-peptide secretory capacity retained the ability to make proinsulin...

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Detalles Bibliográficos
Autores principales: Sims, Emily K., Bahnson, Henry T., Nyalwidhe, Julius, Haataja, Leena, Davis, Asa K., Speake, Cate, DiMeglio, Linda A., Blum, Janice, Morris, Margaret A., Mirmira, Raghavendra G., Nadler, Jerry, Mastracci, Teresa L., Marcovina, Santica, Qian, Wei-Jun, Yi, Lian, Swensen, Adam C., Yip-Schneider, Michele, Schmidt, C. Max, Considine, Robert V., Arvan, Peter, Greenbaum, Carla J., Evans-Molina, Carmella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Pathophysiology/Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341288/
https://www.ncbi.nlm.nih.gov/pubmed/30530850
http://dx.doi.org/10.2337/dc17-2625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341288/
https://www.ncbi.nlm.nih.gov/pubmed/30530850
http://dx.doi.org/10.2337/dc17-2625

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