Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

Parkinson's disease (PD) and multiple system atrophy (MSA) are distinct clinical syndromes characterized by the pathological accumulation of α-synuclein (α-syn) protein fibrils in neurons and glial cells. These disorders and other neurodegenerative diseases may progress via prion-like mechanism...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tritia R., Holmes, Brandon B., Furman, Jennifer L., Dhavale, Dhruva D., Su, Bryant W., Song, Eun-Suk, Cairns, Nigel J., Kotzbauer, Paul T., Diamond, Marc I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341389/
https://www.ncbi.nlm.nih.gov/pubmed/30478174
http://dx.doi.org/10.1074/jbc.RA118.004471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341389/
https://www.ncbi.nlm.nih.gov/pubmed/30478174
http://dx.doi.org/10.1074/jbc.RA118.004471

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