Relevance of CYP2C9 Function in Valproate Therapy

BACKGROUND: Genetic polymorphisms of drug metabolizing enzymes can substantially modify the pharmacokinet-ics of a drug and eventually its efficacy or toxicity; however, inferring a patient’s drug metabolizing capacity merely from his or her genotype can lead to false prediction. Non-genetic host fa...

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Detalles Bibliográficos
Autores principales: Monostory, Katalin, Nagy, Andrea, Tóth, Katalin, Bűdi, Tamás, Kiss, Ádám, Déri, Máté, Csukly, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341495/
https://www.ncbi.nlm.nih.gov/pubmed/29119932
http://dx.doi.org/10.2174/1570159X15666171109143654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341495/
https://www.ncbi.nlm.nih.gov/pubmed/29119932
http://dx.doi.org/10.2174/1570159X15666171109143654

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