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Statins and the Brain: More than Lipid Lowering Agents?

BACKGROUND: Statins represent a class of medications widely prescribed to efficiently treat dyslipidemia. These drugs inhibit 3-βhydroxy 3β-methylglutaryl Coenzyme A reductase (HMGR), the rate-limiting enzyme of mevalonate (MVA) pathway. Besides cholesterol, MVA pathway leads to the production of se...

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Detalles Bibliográficos
Autores principales: Fracassi, Anna, Marangoni, Martina, Rosso, Pamela, Pallottini, Valentina, Fioramonti, Marco, Siteni, Silvia, Segatto, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341496/
https://www.ncbi.nlm.nih.gov/pubmed/28676012
http://dx.doi.org/10.2174/1570159X15666170703101816