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Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients

BACKGROUND: Visceral adipose tissue (VAT) has been identified as the essential fat depot for pathogenetic theories that associateobesity and colon cancer. LINE-1 hypomethylation has been mostly detected in tumor colon tissue, but less is known about the epigenetic pattern in surrounding tissues. The...

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Detalles Bibliográficos
Autores principales: Castellano-Castillo, Daniel, Morcillo, Sonsoles, Crujeiras, Ana B., Sánchez-Alcoholado, Lidia, Clemente-Postigo, Mercedes, Torres, Esperanza, Tinahones, Francisco José, Macias-Gonzalez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341579/
https://www.ncbi.nlm.nih.gov/pubmed/30665376
http://dx.doi.org/10.1186/s12885-018-5226-4