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Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma

BACKGROUND: Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. Recent work in animal models suggests that a critical neuroinflammatory event damages retinal ganglion cell axons in the optic nerve head during ocular hypertensive injury. We previously demonstr...

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Detalles Bibliográficos
Autores principales: Williams, Pete A., Braine, Catherine E., Kizhatil, Krishnakumar, Foxworth, Nicole E., Tolman, Nicholas G., Harder, Jeffrey M., Scott, Rebecca A., Sousa, Gregory L., Panitch, Alyssa, Howell, Gareth R., John, Simon W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341618/
https://www.ncbi.nlm.nih.gov/pubmed/30670050
http://dx.doi.org/10.1186/s13024-018-0303-3