A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity

BACKGROUND: Clinical benefit from checkpoint inhibitors has been associated in a tumor-agnostic manner with two main tumor traits. The first is tumor antigenicity, which is typically measured by tumor mutation burden, microsatellite instability (MSI), or Mismatch Repair Deficiency using gene sequenc...

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Detalles Bibliográficos
Autores principales: Danaher, Patrick, Warren, Sarah, Ong, SuFey, Elliott, Nathan, Cesano, Alessandra, Ferree, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341623/
https://www.ncbi.nlm.nih.gov/pubmed/30665466
http://dx.doi.org/10.1186/s40425-018-0472-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341623/
https://www.ncbi.nlm.nih.gov/pubmed/30665466
http://dx.doi.org/10.1186/s40425-018-0472-1

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