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A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity
BACKGROUND: Clinical benefit from checkpoint inhibitors has been associated in a tumor-agnostic manner with two main tumor traits. The first is tumor antigenicity, which is typically measured by tumor mutation burden, microsatellite instability (MSI), or Mismatch Repair Deficiency using gene sequenc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341623/ https://www.ncbi.nlm.nih.gov/pubmed/30665466 http://dx.doi.org/10.1186/s40425-018-0472-1 |