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A milk-based self-assemble rotavirus VP6–ferritin nanoparticle vaccine elicited protection against the viral infection

BACKGROUND: Rotavirus is the leading cause of severe dehydrating diarrhea in young children and the inner capsid protein VP6 is a potential vaccine candidate that can induce cross-protective immune responses against different Rotavirus strains. The use of ferritin nanoparticles as the scaffold of th...

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Detalles Bibliográficos
Autores principales: Li, Zhipeng, Cui, Kuiqing, Wang, Hong, Liu, Fuhang, Huang, Kongwei, Duan, Zhaojun, Wang, Fengchao, Shi, Deshun, Liu, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341625/
https://www.ncbi.nlm.nih.gov/pubmed/30670042
http://dx.doi.org/10.1186/s12951-019-0446-6