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A milk-based self-assemble rotavirus VP6–ferritin nanoparticle vaccine elicited protection against the viral infection
BACKGROUND: Rotavirus is the leading cause of severe dehydrating diarrhea in young children and the inner capsid protein VP6 is a potential vaccine candidate that can induce cross-protective immune responses against different Rotavirus strains. The use of ferritin nanoparticles as the scaffold of th...
Autores principales: | Li, Zhipeng, Cui, Kuiqing, Wang, Hong, Liu, Fuhang, Huang, Kongwei, Duan, Zhaojun, Wang, Fengchao, Shi, Deshun, Liu, Qingyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341625/ https://www.ncbi.nlm.nih.gov/pubmed/30670042 http://dx.doi.org/10.1186/s12951-019-0446-6 |
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