NEP(1-40)-modified human serum albumin nanoparticles enhance the therapeutic effect of methylprednisolone against spinal cord injury

BACKGROUND: Frequent injection of high-dose methylprednisolone (MP) is used to treat spinal cord injury (SCI), but free MP is associated with various side effects and its water solubility is low, limiting potential dosing regimes and administration routes. Albumin-based nanoparticles, which can enca...

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Detalles Bibliográficos
Autores principales: Lin, Yan, Li, Chunhong, Li, Jian, Deng, Ruolan, Huang, Juan, Zhang, Qinglian, Lyu, Jiayao, Hao, Na, Zhong, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341626/
https://www.ncbi.nlm.nih.gov/pubmed/30670038
http://dx.doi.org/10.1186/s12951-019-0449-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341626/
https://www.ncbi.nlm.nih.gov/pubmed/30670038
http://dx.doi.org/10.1186/s12951-019-0449-3

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