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CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan

BACKGROUND: The effectiveness of autologous haematopoietic stem cell transplantation (auto-HSCT) in treating severe systemic sclerosis (SSc) is established; however, the necessity of purified CD34+ cell grafts and the appropriate conditioning regimen remain unclear. This study aimed to compare the e...

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Detalles Bibliográficos
Autores principales: Ayano, Masahiro, Tsukamoto, Hiroshi, Mitoma, Hiroki, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Miyamoto, Toshihiro, Horiuchi, Takahiko, Niiro, Hiroaki, Nagafuji, Koji, Harada, Mine, Akashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341635/
https://www.ncbi.nlm.nih.gov/pubmed/30670057
http://dx.doi.org/10.1186/s13075-019-1823-0