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Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data
We perform a large-scale RNA sequencing study to experimentally identify genes that are downregulated by 25 miRNAs. This RNA-seq dataset is combined with public miRNA target binding data to systematically identify miRNA targeting features that are characteristic of both miRNA binding and target down...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341724/ https://www.ncbi.nlm.nih.gov/pubmed/30670076 http://dx.doi.org/10.1186/s13059-019-1629-z |