Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA

Endonuclease IV (EndoIV) is a DNA damage-specific endonuclease that mainly hydrolyzes the phosphodiester bond located at 5′ of an apurinic/apyrimidinic (AP) site in DNA. EndoIV also possesses 3′-exonuclease activity for removing 3′-blocking groups and normal nucleotides. Here, we report that Thermoc...

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Detalles Bibliográficos
Autores principales: Wang, Wei-Wei, Zhou, Huan, Xie, Juan-Juan, Yi, Gang-Shun, He, Jian-Hua, Wang, Feng-Ping, Xiao, Xiang, Liu, Xi-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341776/
https://www.ncbi.nlm.nih.gov/pubmed/30586940
http://dx.doi.org/10.3390/ijms20010069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341776/
https://www.ncbi.nlm.nih.gov/pubmed/30586940
http://dx.doi.org/10.3390/ijms20010069

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