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The tumor suppressor OVCA1 is a short half-life protein degraded by the ubiquitin-proteasome pathway
Ovarian cancer gene 1 (OVCA1) is a tumor suppressor associated with ovarian cancer, which is involved in cell proliferation regulation, embryonic development and tumorigenesis. Loss of heterozygosity in the OVCA1 gene occurs in 50–86% of cases of ovarian cancer; however, the physiological and bioche...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341780/ https://www.ncbi.nlm.nih.gov/pubmed/30675298 http://dx.doi.org/10.3892/ol.2018.9852 |