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SOX2 knockdown inhibits the migration and invasion of basal cell carcinoma cells by targeting the SRPK1-mediated PI3K/AKT signaling pathway

Basal cell carcinoma (BCC) is the most common type of human skin cancer, which is driven by the aberrant activation of Hedgehog signaling. Previous evidence indicated that sex determining region Y-box 2 (SOX2) is associated with the tumor metastasis. However, the expression and role of SOX2 in BCC r...

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Detalles Bibliográficos
Autores principales: Li, Zhuo-Ran, Jiang, Yong, Hu, Jian-Zhong, Chen, Yang, Liu, Quan-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341784/
https://www.ncbi.nlm.nih.gov/pubmed/30675221
http://dx.doi.org/10.3892/ol.2018.9810