CRISPR/Cas9-mediated cervical cancer treatment targeting human papillomavirus E6

High-risk human papillomavirus (HPV) is a common cause of cervical cancer. HPV E6 oncoprotein promotes the degradation of host tumor suppressor gene p53, leading to the development of tumors. Therapeutic strategies that specifically target E6, which is constitutively expressed in tumors and is not p...

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Detalles Bibliográficos
Autores principales: Yoshiba, Takahiro, Saga, Yasushi, Urabe, Masashi, Uchibori, Ryosuke, Matsubara, Shigeki, Fujiwara, Hiroyuki, Mizukami, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341785/
https://www.ncbi.nlm.nih.gov/pubmed/30675284
http://dx.doi.org/10.3892/ol.2018.9815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341785/
https://www.ncbi.nlm.nih.gov/pubmed/30675284
http://dx.doi.org/10.3892/ol.2018.9815

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