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CRISPR/Cas9-mediated cervical cancer treatment targeting human papillomavirus E6
High-risk human papillomavirus (HPV) is a common cause of cervical cancer. HPV E6 oncoprotein promotes the degradation of host tumor suppressor gene p53, leading to the development of tumors. Therapeutic strategies that specifically target E6, which is constitutively expressed in tumors and is not p...
Autores principales: | Yoshiba, Takahiro, Saga, Yasushi, Urabe, Masashi, Uchibori, Ryosuke, Matsubara, Shigeki, Fujiwara, Hiroyuki, Mizukami, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341785/ https://www.ncbi.nlm.nih.gov/pubmed/30675284 http://dx.doi.org/10.3892/ol.2018.9815 |
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