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Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma

Research on mevalonate kinase deficiency has revealed that it may lead to the development of renal angiomyolipomas (RAMLs). Thus, it was suspected that geranylgeranyl pyrophosphate synthase (GGPPS), a key enzyme in the mevalonate pathway, may be involved in the development of RAMLs. In the present s...

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Detalles Bibliográficos
Autores principales: Zhao, Dan-Dan, Yuan, Jun, Cheng, Qi, Qi, Ya-Ling, Lu, Ke, Lai, Shan-Shan, Sun, Qian, Zhao, Yue, Fang, Lei, Jin, Mei-Ling, Yu, De-Cai, Qiu, Yu-Dong, Li, Chao-Jun, Chen, Jun, Xue, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341897/
https://www.ncbi.nlm.nih.gov/pubmed/30675208
http://dx.doi.org/10.3892/ol.2018.9808