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Effects of low-dose ketamine infusion on remifentanil-induced acute opioid tolerance and the inflammatory response in patients undergoing orthognathic surgery

PURPOSE: Remifentanil is associated with acute opioid tolerance that can lead to increased postoperative consumption of opioid analgesics. The purpose of this study was to determine whether a low dose of ketamine prevents remifentanil-induced acute opioid tolerance and affects the neutrophil–lymphoc...

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Detalles Bibliográficos
Autores principales: Kido, Kanta, Toda, Shinichi, Shindo, Yuki, Miyashita, Hitoshi, Sugino, Shigekazu, Masaki, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342226/
https://www.ncbi.nlm.nih.gov/pubmed/30705603
http://dx.doi.org/10.2147/JPR.S177098