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Electrocardiographic Effects of a Supratherapeutic Dose of WCK 2349, a Benzoquinolizine Fluoroquinolone

The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a supratherapeutic oral dose of 2,600 mg. A total of 48 healthy volunteers were randomized to treatment with placebo, WCK 2349, or oral moxifloxacin, 400 m...

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Detalles Bibliográficos
Autores principales: Mason, Jay W., Chugh, Rakesh, Patel, Anasuya, Gutte, Ranjeet, Bhatia, Ashima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342240/
https://www.ncbi.nlm.nih.gov/pubmed/30369076
http://dx.doi.org/10.1111/cts.12594