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Role of tau N-terminal motif in the secretion of human tau by End Binding proteins

For unknown reasons, humans appear to be particular susceptible to developing tau pathology leading to neurodegeneration. Transgenic mice are still undoubtedly the most popular and extensively used animal models for studying Alzheimer’s disease and other tauopathies. While these murine models genera...

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Detalles Bibliográficos
Autores principales: Sayas, C. Laura, Medina, Miguel, Cuadros, Raquel, Ollá, Ivanna, García, Esther, Pérez, Mar, Ferrer, Isidro, Hernández, Félix, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342323/
https://www.ncbi.nlm.nih.gov/pubmed/30668577
http://dx.doi.org/10.1371/journal.pone.0210864