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Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting
Extensive cell-to-cell variation exists even among putatively identical cells, and there is great interest in understanding how the properties of transcription relate to this heterogeneity. Differential expression from the two gene copies in diploid cells could potentially contribute, yet our abilit...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342324/ https://www.ncbi.nlm.nih.gov/pubmed/30625149 http://dx.doi.org/10.1371/journal.pgen.1007874 |