Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization

Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation. How TGFβ signaling to microglia influences pathologi...

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Detalles Bibliográficos
Autores principales: Ma, Wenxin, Silverman, Sean M, Zhao, Lian, Villasmil, Rafael, Campos, Maria M, Amaral, Juan, Wong, Wai T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342522/
https://www.ncbi.nlm.nih.gov/pubmed/30666961
http://dx.doi.org/10.7554/eLife.42049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342522/
https://www.ncbi.nlm.nih.gov/pubmed/30666961
http://dx.doi.org/10.7554/eLife.42049

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