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The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation

Human primordial germ cells (hPGCs) are the first embryonic progenitors in the germ cell lineage, yet the molecular mechanisms required for hPGC formation are not well characterized. To identify regulatory regions in hPGC development, we used the assay for transposase-accessible chromatin using sequ...

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Detalles Bibliográficos
Autores principales: Chen, Di, Liu, Wanlu, Zimmerman, Jill, Pastor, William A., Kim, Rachel, Hosohama, Linzi, Ho, Jamie, Aslanyan, Marianna, Gell, Joanna J., Jacobsen, Steven E., Clark, Amander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342560/
https://www.ncbi.nlm.nih.gov/pubmed/30590035
http://dx.doi.org/10.1016/j.celrep.2018.12.011