Silencing the PIK3CA Gene Enhances the Sensitivity of Childhood Leukemia Cells to Chemotherapy Drugs by Suppressing the Phosphorylation of Akt

PURPOSE: This study aimed to investigate the effects of PIK3CA on the sensitivity of acute B lymphocytic leukemia cells (Nalm-6 cells) to chemotherapy drugs. MATERIALS AND METHODS: Children's normal B lymphocytes and Nalm-6 cells were cultured. Nalm-6 cells were transfected with PIK3CA siRNA (s...

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Detalles Bibliográficos
Autores principales: Liang, Xiuling, Xin, Xianfang, Qi, Dongmei, Fu, Chengyan, Ding, Mingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342719/
https://www.ncbi.nlm.nih.gov/pubmed/30666840
http://dx.doi.org/10.3349/ymj.2019.60.2.182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342719/
https://www.ncbi.nlm.nih.gov/pubmed/30666840
http://dx.doi.org/10.3349/ymj.2019.60.2.182

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