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Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC–MS and ion mobility enabled HILIC–MS

INTRODUCTION: As large scale metabolic phenotyping is increasingly employed in preclinical studies and in the investigation of human health and disease the current LC–MS/MS profiling methodologies adopted for large sample sets can result in lengthy analysis times, putting strain on available resourc...

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Detalles Bibliográficos
Autores principales: King, Adam M., Mullin, Lauren G., Wilson, Ian D., Coen, Muireann, Rainville, Paul D., Plumb, Robert S., Gethings, Lee A., Maker, Garth, Trengove, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342856/
https://www.ncbi.nlm.nih.gov/pubmed/30830424
http://dx.doi.org/10.1007/s11306-019-1474-9