The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study

AIMS/HYPOTHESIS: The extent to which effects of BMI on CHD are mediated by glycaemic and lipid risk factors is unclear. In this study we examined the effects of these traits using genetic evidence. METHODS: We used two-sample Mendelian randomisation to determine: (1) the causal effect of BMI on CHD...

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Detalles Bibliográficos
Autores principales: Xu, Lin, Borges, Maria Carolina, Hemani, Gibran, Lawlor, Debbie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342872/
https://www.ncbi.nlm.nih.gov/pubmed/28889241
http://dx.doi.org/10.1007/s00125-017-4396-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342872/
https://www.ncbi.nlm.nih.gov/pubmed/28889241
http://dx.doi.org/10.1007/s00125-017-4396-y

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