Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9

CRISPR-Cas9 is a powerful gene editing technique that can induce mutations in a target gene of interest in almost any mammalian cell line. However, its practicality can be limited if target cell lines are difficult to transfect and do not proliferate. In the current study, we have developed a stream...

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Detalles Bibliográficos
Autores principales: Jin, Yuan-Hu, Joo, Hyunjeong, Lee, Kwangjun, Kim, Hyeongseok, Didier, Ruth, Yang, Young, Shin, Heungsop, Lee, Choogon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342919/
https://www.ncbi.nlm.nih.gov/pubmed/30670765
http://dx.doi.org/10.1038/s41598-018-36736-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342919/
https://www.ncbi.nlm.nih.gov/pubmed/30670765
http://dx.doi.org/10.1038/s41598-018-36736-y

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