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Septin filament coalignment with microtubules depends on SEPT9_i1 and tubulin polyglutamylation, and is an early feature of acquired cell resistance to paclitaxel

Cancer cell resistance to taxanes is a complex, multifactorial process, which results from the combination of several molecular and cellular changes. In breast cancer cells adapted to long-term paclitaxel treatment, we previously identified a new adaptive mechanism that contributes to resistance and...

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Detalles Bibliográficos
Autores principales: Targa, Benjamin, Klipfel, Laurence, Cantaloube, Isabelle, Salameh, Joëlle, Benoit, Béatrice, Poüs, Christian, Baillet, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342940/
https://www.ncbi.nlm.nih.gov/pubmed/30670682
http://dx.doi.org/10.1038/s41419-019-1318-6