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Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

Lymph node metastasis is of major prognostic significance for breast cancer. Lymph node metastasis arises at a very early stage in some patients. Using the data downloaded from the TCGA database, we studied the differences between primary tumors with and without lymph node metastasis at the multi-om...

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Detalles Bibliográficos
Autores principales: Wang, Zhigang, Liu, Wei, Chen, Chong, Yang, Xiaolin, Luo, Yunping, Zhang, Bailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342949/
https://www.ncbi.nlm.nih.gov/pubmed/30670769
http://dx.doi.org/10.1038/s41598-018-36319-x