Cargando…

Oncofoetal insulin receptor isoform A marks the tumour endothelium; an underestimated pathway during tumour angiogenesis and angiostatic treatment

BACKGROUND: In a genomic screen for determinants of the tumour vasculature, we identified insulin receptor (INSR) to mark the tumour endothelium. As a functional role for insulin/INSR in cancer has been suggested and markers of the tumour endothelium may be attractive therapeutic targets, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nowak-Sliwinska, Patrycja, van Beijnum, Judy R., Huijbers, Elisabeth J. M., Gasull, Paula C., Mans, Laurie, Bex, Axel, Griffioen, Arjan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342959/ https://www.ncbi.nlm.nih.gov/pubmed/30559346 http://dx.doi.org/10.1038/s41416-018-0347-8

Ejemplares similares

A genomic screen for angiosuppressor genes in the tumor endothelium identifies a multifaceted angiostatic role for bromodomain containing 7 (BRD7)
por: van Beijnum, Judy R., et al.
Publicado: (2017)

Angiostatic vaccines, an underestimated approach of cancer therapy
por: Griffioen, Arjan W.
Publicado: (2014)

Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion
por: Nowak-Sliwinska, Patrycja, et al.
Publicado: (2012)

Low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy for cancer: lack of vascular normalization
por: Weiss, Andrea, et al.
Publicado: (2014)

Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer
por: Weiss, Andrea, et al.
Publicado: (2015)

Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy
por: Weiss, Andrea, et al.
Publicado: (2015)

NF-κB: a new player in angiostatic therapy
por: Tabruyn, Sebastien P., et al.
Publicado: (2008)

Erratum to: miRNAs: micro-managers of anticancer combination therapies
por: van Beijnum, Judy R., et al.
Publicado: (2017)

miRNAs: micro-managers of anticancer combination therapies
por: van Beijnum, Judy R., et al.
Publicado: (2017)

Photoactivation of lysosomally sequestered sunitinib after angiostatic treatment causes vascular occlusion and enhances tumor growth inhibition
por: Nowak-Sliwinska, P, et al.
Publicado: (2015)

Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth
por: Lefesvre, Pierre, et al.
Publicado: (2002)

Identification of a common oncofoetal protein in x-ray and chemically induced rat gastrointestinal tumours.
por: Stevens, R. H., et al.
Publicado: (1981)

Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane
por: Nowak-Sliwinska, Patrycja, et al.
Publicado: (2010)

Oncofoetal fibronectin – a tumour-specific marker in detecting minimal residual disease in differentiated thyroid carcinoma
por: Hesse, E, et al.
Publicado: (2005)

Combination of ruthenium(II)-arene complex [Ru(η(6)-p-cymene)Cl(2)(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity
por: Berndsen, Robert H., et al.
Publicado: (2017)

The tumor vasculature an attractive CAR T cell target in solid tumors
por: Akbari, Parvin, et al.
Publicado: (2019)

Oncofoetal antigens in cancer of the cervix and ovary.
por: Cauchi, M. N., et al.
Publicado: (1981)

Another oncofoetal antigen in colonic carcinoma.
por: Ma, J., et al.
Publicado: (1980)

Tumour vascularization: sprouting angiogenesis and beyond
por: Hillen, Femke, et al.
Publicado: (2007)

Apoptosis on the move
por: Nowak-Sliwinska, Patrycja, et al.
Publicado: (2018)

Programmed cell death lives
por: Griffioen, Arjan W., et al.
Publicado: (2022)

Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy
por: van Beijnum, Judy R., et al.
Publicado: (2022)

Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
por: Nowak-Sliwinska, Patrycja, et al.
Publicado: (2022)

A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma
por: Shaw, D M, et al.
Publicado: (2007)

Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment
por: van Beijnum, Judy R., et al.
Publicado: (2020)

Oncofoetal antigen I: a target for immune cytolysis of human cancer.
por: Sidell, N., et al.
Publicado: (1979)

Erratum: Berndsen, R.H., et al. Colorectal Cancer Growth Retardation through Induction of Apoptosis, Using an Optimized Synergistic Cocktail of Axitinib, Erlotinib, and Dasatinib, Cancers 2019, 11, 1878
por: Berndsen, Robert H., et al.
Publicado: (2020)

Colorectal Cancer Growth Retardation through Induction of Apoptosis, Using an Optimized Synergistic Cocktail of Axitinib, Erlotinib, and Dasatinib
por: Berndsen, Robert H., et al.
Publicado: (2019)

Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect
por: Kleibeuker, Esther A., et al.
Publicado: (2016)

Expression of oncofoetal pancreatic antigens in hamster adult pancreas during experimental carcinogenesis.
por: Escribano, M. J., et al.
Publicado: (1985)

5T4 oncofoetal glycoprotein: an old target for a novel prostate cancer immunotherapy
por: Cappuccini, Federica, et al.
Publicado: (2017)

Angiogenic and angiostatic factors present in the saliva of malaria patients
por: Lekpor, Cecilia Elorm, et al.
Publicado: (2022)

Ectopic Spleen Tissue – an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour
por: Grambow, Eberhard, et al.
Publicado: (2015)

Adhesion of tumour-infiltrating lymphocytes to endothelium: a phenotypic and functional analysis.
por: Adams, D. H., et al.
Publicado: (1997)

Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters
por: Nazarov, Alexey A., et al.
Publicado: (2013)

Proteomic profiling of endorepellin angiostatic activity on human endothelial cells
por: Zoeller, Jason J, et al.
Publicado: (2008)

Antitumor and Angiostatic Activities of the Antimicrobial Peptide Dermaseptin B2
por: van Zoggel, Hanneke, et al.
Publicado: (2012)

A case of markedly impaired wound repair with angiostatic pazopanib in a patient who had Mohs surgery for a basal cell carcinoma
por: Nahm, William J, et al.
Publicado: (2023)

In vivo evaluation of small-molecule thermoresponsive anticancer drugs potentiated by hyperthermia
por: Clavel, Catherine M., et al.
Publicado: (2015)

The response of VEGF-stimulated endothelial cells to angiostatic molecules is substrate-dependent
por: Addison, Christina L, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_qudskius05g64t6vb729v6arl0