Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis

Physiological stress conditions attenuate global mRNA translation via modifications of key eukaryotic initiation factors. However, non-canonical translation initiation mechanisms allow cap-independent translation of certain mRNAs. We have previously demonstrated that eIF5B promotes cap-independent t...

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Detalles Bibliográficos
Autores principales: Ross, Joseph A., Dungen, Keiran Vanden, Bressler, Kamiko R., Fredriksen, Mikayla, Khandige Sharma, Divya, Balasingam, Nirujah, Thakor, Nehal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342974/
https://www.ncbi.nlm.nih.gov/pubmed/30670698
http://dx.doi.org/10.1038/s41419-018-1283-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342974/
https://www.ncbi.nlm.nih.gov/pubmed/30670698
http://dx.doi.org/10.1038/s41419-018-1283-5

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