Partial depletion of dopaminergic neurons in the substantia nigra impairs olfaction and alters neural activity in the olfactory bulb

Olfactory dysfunction is a major non-motor symptom that appears during the early stages of Parkinson’s Disease (PD), a neurodegenerative disorder characterized by loss of dopaminergic neurons in the substantia nigra (SN). Depletion of SN dopaminergic neurons by 6-hydroxydopamine (6-OHDA) is widely u...

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Detalles Bibliográficos
Autores principales: Zhang, Wenfeng, Sun, Changcheng, Shao, Yufeng, Zhou, Zheng, Hou, Yiping, Li, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342975/
https://www.ncbi.nlm.nih.gov/pubmed/30670747
http://dx.doi.org/10.1038/s41598-018-36538-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342975/
https://www.ncbi.nlm.nih.gov/pubmed/30670747
http://dx.doi.org/10.1038/s41598-018-36538-2

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