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Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity
The mouse Major Urinary Proteins (MUPs) contain a conserved β-barrel structure with a characteristic central hydrophobic pocket that binds a variety of volatile compounds. After release of urine, these molecules are slowly emitted in the environment where they play an important role in chemical comm...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342991/ https://www.ncbi.nlm.nih.gov/pubmed/30670733 http://dx.doi.org/10.1038/s41598-018-36391-3 |